https://kalper.net/kp/tag/epidemics/ Epidemics Wowchemy (https://wowchemy.com)en-usSat, 01 Jan 2022 00:00:00 +0000 https://kalper.net/kp/media/logo_hu7c4e9283a16f91dce013794dd725bda5_36458_300x300_fit_lanczos_3.png https://kalper.net/kp/tag/epidemics/ https://kalper.net/kp/items/projects/epiclone/ Sat, 01 Jan 2022 00:00:00 +0000 https://kalper.net/kp/items/projects/epiclone/ <p><strong>Cloned simulations of epidemiological outbreaks</strong> like COVID-19 can now rapidly evaluate <strong>millions</strong> of what-if scenarios at national and world scales, and efficiently exploit <strong>1000s of GPUs</strong>.</p> <figure id="figure-epiclone-model-elements"> <div class="d-flex justify-content-center"> <div class="w-100" ><img alt="EpiClone model elements" srcset=" /kp/items/projects/epiclone/featured_hu7f44203ba5f2749f71b353c721dff248_1187578_055d89a1f206d3f37f77d5950f46dfa5.png 400w, /kp/items/projects/epiclone/featured_hu7f44203ba5f2749f71b353c721dff248_1187578_b54b17023704f6ea95d4370a9dd5e412.png 760w, /kp/items/projects/epiclone/featured_hu7f44203ba5f2749f71b353c721dff248_1187578_1200x1200_fit_lanczos_3.png 1200w" src="https://kalper.net/kp/kp/items/projects/epiclone/featured_hu7f44203ba5f2749f71b353c721dff248_1187578_055d89a1f206d3f37f77d5950f46dfa5.png" width="760" height="410" loading="lazy" data-zoomable /></div> </div><figcaption> EpiClone model elements </figcaption></figure> <figure id="figure-epiclone-simulating-usa-scenarios"> <div class="d-flex justify-content-center"> <div class="w-100" ><img alt="EpiClone simulating USA scenarios" srcset=" /kp/items/projects/epiclone/images/EpiClone-USA_hud748f19d2dbeaf487bf3d65f6f1c3474_180141_15325061cd0113e685d7d66da80b0795.png 400w, /kp/items/projects/epiclone/images/EpiClone-USA_hud748f19d2dbeaf487bf3d65f6f1c3474_180141_ceb147250939b2984d6c7308a03a3916.png 760w, /kp/items/projects/epiclone/images/EpiClone-USA_hud748f19d2dbeaf487bf3d65f6f1c3474_180141_1200x1200_fit_lanczos_3.png 1200w" src="https://kalper.net/kp/kp/items/projects/epiclone/images/EpiClone-USA_hud748f19d2dbeaf487bf3d65f6f1c3474_180141_15325061cd0113e685d7d66da80b0795.png" width="760" height="556" loading="lazy" data-zoomable /></div> </div><figcaption> EpiClone simulating USA scenarios </figcaption></figure> <h2 id="overview">Overview</h2> <p><strong>EpiClone</strong> represents the next advancements in what-if decision evaluation on state-of-the-art accelerated computing platforms including supercomputers containing thousands of GPUs.</p> <p><strong>EpiClone</strong> addresses global epidemiological outbreaks via an incremental simulation-based what-if decision tree evolution. <strong>EpiClone</strong> offers new scaling capabilities that were previously not possible before for rapidly simulating thousands or millions of epidemiological scenarios.</p> <p>The <strong>EpiClone</strong> approach and results in scalable modeling and fast scenario exploration provide a leap in the analyses of epidemics and other complex systems.</p> <h2 id="gallery">Gallery</h2> <div class="gallery" style="text-align: center;"> <a data-fancybox="gallery-EpiClone" href="https://kalper.net/kp/kp/items/projects/epiclone/images/EpiClone-India.png" > <img src="https://kalper.net/kp/kp/items/projects/epiclone/images/EpiClone-India_huf2a9648f84b05d3b2165748f11dbe3aa_243142_500x0_resize_q90_lanczos_3.png" loading="lazy" alt="EpiClone-India.png" width="500" height="366"> </a> <a data-fancybox="gallery-EpiClone" href="https://kalper.net/kp/kp/items/projects/epiclone/images/EpiClone-UK.png" > <img src="https://kalper.net/kp/kp/items/projects/epiclone/images/EpiClone-UK_hu832a7eed8545e0917a825d145f60ff96_263218_500x0_resize_q90_lanczos_3.png" loading="lazy" alt="EpiClone-UK.png" width="500" height="366"> </a> <a data-fancybox="gallery-EpiClone" href="https://kalper.net/kp/kp/items/projects/epiclone/images/EpiClone-USA.png" > <img src="https://kalper.net/kp/kp/items/projects/epiclone/images/EpiClone-USA_hud748f19d2dbeaf487bf3d65f6f1c3474_180141_500x0_resize_q90_lanczos_3.png" loading="lazy" alt="EpiClone-USA.png" width="500" height="366"> </a> <a data-fancybox="gallery-EpiClone" href="https://kalper.net/kp/kp/items/projects/epiclone/images/epi-model-overview.png" > <img src="https://kalper.net/kp/kp/items/projects/epiclone/images/epi-model-overview_hu7f44203ba5f2749f71b353c721dff248_1187578_500x0_resize_q90_lanczos_3.png" loading="lazy" alt="epi-model-overview.png" width="500" height="270"> </a> <a data-fancybox="gallery-EpiClone" href="https://kalper.net/kp/kp/items/projects/epiclone/images/epi-model-ptts-people.png" > <img src="https://kalper.net/kp/kp/items/projects/epiclone/images/epi-model-ptts-people_hu0e6e8f75fb4a2a9aebb39e6d60c2da24_1927846_500x0_resize_q90_lanczos_3.png" loading="lazy" alt="epi-model-ptts-people.png" width="500" height="241"> </a> <a data-fancybox="gallery-EpiClone" href="https://kalper.net/kp/kp/items/projects/epiclone/images/epiclone-equations.png" > <img src="https://kalper.net/kp/kp/items/projects/epiclone/images/epiclone-equations_hub8eada6fc8beafa09ff9d59d14fa5e36_137085_500x0_resize_q90_lanczos_3.png" loading="lazy" alt="epiclone-equations.png" width="500" height="351"> </a> </div> <h2 id="organization">Organization</h2> <ul> <li><strong>Sponsor</strong>: Lab Directed Research and Development, Oak Ridge National Laboratory</li> <li><strong>Period</strong>: 2015-2017</li> </ul> <h2 id="related-publications">Related Publications</h2> <p> <div class="media stream-item"> <div class="media-body"> <div class="section-subheading article-title mb-0 mt-0"> <a href="https://kalper.net/kp/kp/publication/2018-01-31-tomacs-clonex/" >Scalable Cloning on Large-Scale GPU Platforms with Application to Time-Stepped Simulations on Grids</a> </div> <a href="https://kalper.net/kp/kp/publication/2018-01-31-tomacs-clonex/" class="summary-link"> <div class="article-style"> Cloning is a technique to efficiently simulate a tree of multiple what-if scenarios that are unraveled during the course of a base simulation. We present the conceptual simulation framework, algorithmic foundations, and runtime interface of CloneX, a new system we designed for scalable simulation cloning. </div> </a> <div class="stream-meta article-metadata"> <div> <span > <a href="https://kalper.net/kp/kp/author/srikanth-yoginath/">Srikanth Yoginath</a></span>, <span class="author-highlighted"> <a href="https://kalper.net/kp/kp/author/kalyan-perumalla/">Kalyan Perumalla</a></span> </div> </div> <div class="btn-links"> <a class="btn btn-outline-primary btn-page-header btn-sm" href="https://kalper.net/kp/kp/publication/2018-01-31-tomacs-clonex/2018-01-31-tomacs-clonex.pdf" target="_blank" rel="noopener"> PDF </a> <a href="#" class="btn btn-outline-primary btn-page-header btn-sm js-cite-modal" data-filename="/kp/publication/2018-01-31-tomacs-clonex/cite.bib"> Cite </a> <a class="btn btn-outline-primary btn-page-header btn-sm" href="https://doi.org/10.1145/3158669" target="_blank" rel="noopener"> DOI </a> </div> </div> <div class="ml-3"> <a href="https://kalper.net/kp/kp/publication/2018-01-31-tomacs-clonex/" > <img src="https://kalper.net/kp/kp/publication/2018-01-31-tomacs-clonex/featured_hu20b141de93ff3b461a57fa9778737dd6_599196_150x0_resize_lanczos_3.png" alt="Scalable Cloning on Large-Scale GPU Platforms with Application to Time-Stepped Simulations on Grids" loading="lazy"> </a> </div> </div> <div class="media stream-item"> <div class="media-body"> <div class="section-subheading article-title mb-0 mt-0"> <a href="https://kalper.net/kp/kp/publication/2021-07-01-jiisc-epiclone/" >Mesoscopic Modeling and Rapid Simulation of Incremental Changes in Epidemic Scenarios on GPUs: Fast What–If Analyses of Localized and Dynamic Effects</a> </div> <a href="https://kalper.net/kp/kp/publication/2021-07-01-jiisc-epiclone/" class="summary-link"> <div class="article-style"> A mesoscopic modeling approach is described that strikes a middle ground between macroscopic models based on coupled differential equations and microscopic models built on fine-grained behaviors at the individual entity level. Execution of our implementation scaled to 8192 GPUs of supercomputing platforms demonstrates the ability to rapidly evaluate what–if scenarios several orders of magnitude faster than the conventional methods. </div> </a> <div class="stream-meta article-metadata"> <div> <span class="author-highlighted"> <a href="https://kalper.net/kp/kp/author/kalyan-perumalla/">Kalyan Perumalla</a></span>, <span > <a href="https://kalper.net/kp/kp/author/maksudul-alam/">Maksudul Alam</a></span> </div> </div> <div class="btn-links"> <a class="btn btn-outline-primary btn-page-header btn-sm" href="https://kalper.net/kp/kp/publication/2021-07-01-jiisc-epiclone/2021-07-01-JIISC-EpiClone.pdf" target="_blank" rel="noopener"> PDF </a> <a href="#" class="btn btn-outline-primary btn-page-header btn-sm js-cite-modal" data-filename="/kp/publication/2021-07-01-jiisc-epiclone/cite.bib"> Cite </a> <a class="btn btn-outline-primary btn-page-header btn-sm" href="https://doi.org/10.1007/s41745-021-00253-1" target="_blank" rel="noopener"> DOI </a> </div> </div> <div class="ml-3"> <a href="https://kalper.net/kp/kp/publication/2021-07-01-jiisc-epiclone/" > <img src="https://kalper.net/kp/kp/publication/2021-07-01-jiisc-epiclone/featured_hud748f19d2dbeaf487bf3d65f6f1c3474_180141_150x0_resize_lanczos_3.png" alt="Mesoscopic Modeling and Rapid Simulation of Incremental Changes in Epidemic Scenarios on GPUs: Fast What–If Analyses of Localized and Dynamic Effects" loading="lazy"> </a> </div> </div> <div class="media stream-item"> <div class="media-body"> <div class="section-subheading article-title mb-0 mt-0"> <a href="https://kalper.net/kp/kp/publication/pub-115-epi-tsmsi11/" >Discrete Event Modeling and Massively Parallel Execution of Epidemic Outbreak Phenomena</a> </div> <a href="https://kalper.net/kp/kp/publication/pub-115-epi-tsmsi11/" class="summary-link"> <div class="article-style"> In complex phenomena such as epidemiological outbreaks, the intensity of inherent feedback effects a&hellip; </div> </a> <div class="stream-meta article-metadata"> <div> <span class="author-highlighted"> <a href="https://kalper.net/kp/kp/author/kalyan-perumalla/">Kalyan Perumalla</a></span>, <span > <a href="https://kalper.net/kp/kp/author/sudip-seal/">Sudip Seal</a></span> </div> </div> <div class="btn-links"> <a class="btn btn-outline-primary btn-page-header btn-sm" href="https://kalper.net/kp/kp/publication/pub-115-epi-tsmsi11/pub-115-epi-tsmsi11.pdf" target="_blank" rel="noopener"> PDF </a> <a href="#" class="btn btn-outline-primary btn-page-header btn-sm js-cite-modal" data-filename="/kp/publication/pub-115-epi-tsmsi11/cite.bib"> Cite </a> </div> </div> <div class="ml-3"> <a href="https://kalper.net/kp/kp/publication/pub-115-epi-tsmsi11/" > <img src="https://kalper.net/kp/kp/publication/pub-115-epi-tsmsi11/featured_hu45dd75ea29cf834a1ef4a36772fd91e3_44052_150x0_resize_q75_lanczos.jpg" alt="Discrete Event Modeling and Massively Parallel Execution of Epidemic Outbreak Phenomena" loading="lazy"> </a> </div> </div> <div class="media stream-item"> <div class="media-body"> <div class="section-subheading article-title mb-0 mt-0"> <a href="https://kalper.net/kp/kp/publication/pub-108-epi-pads10/" >Reversible Parallel Discrete-Event Execution of Large-scale Epidemic Outbreak Models</a> </div> <a href="https://kalper.net/kp/kp/publication/pub-108-epi-pads10/" class="summary-link"> <div class="article-style"> The spatial scale, runtime speed, and behavioral detail of epidemic outbreak simulations altogether &hellip; </div> </a> <div class="stream-meta article-metadata"> <div> <span class="author-highlighted"> <a href="https://kalper.net/kp/kp/author/kalyan-perumalla/">Kalyan Perumalla</a></span>, <span > <a href="https://kalper.net/kp/kp/author/sudip-seal/">Sudip Seal</a></span> </div> </div> <div class="btn-links"> <a class="btn btn-outline-primary btn-page-header btn-sm" href="https://kalper.net/kp/kp/publication/pub-108-epi-pads10/pub-108-epi-pads10.pdf" target="_blank" rel="noopener"> PDF </a> <a href="#" class="btn btn-outline-primary btn-page-header btn-sm js-cite-modal" data-filename="/kp/publication/pub-108-epi-pads10/cite.bib"> Cite </a> <a class="btn btn-outline-primary btn-page-header btn-sm" href="https://kalper.net/kp/pubdocs/epi-pads10-slides.pdf" target="_blank" rel="noopener"> Slides </a> </div> </div> <div class="ml-3"> <a href="https://kalper.net/kp/kp/publication/pub-108-epi-pads10/" > <img src="https://kalper.net/kp/kp/publication/pub-108-epi-pads10/featured_hu8e43e3813741e1258030865fa716d416_21712_150x0_resize_q75_lanczos.jpg" alt="Reversible Parallel Discrete-Event Execution of Large-scale Epidemic Outbreak Models" loading="lazy"> </a> </div> </div> </p>